MACS (MAGNETIC-ACTIVATED CELL SORTING ) – NEW GENERATION OF BEST-QUALITY SPERM SELECTION
MACS- system is an efficient method to selectfunctional sperm and improve pregnancy rates.
MACS Annexin V System was designed to selectively remove these defective although morphologically indistinguishable cells from sperm preparations. The procedure begins with magnetic labeling of unwanted cells and then, they are passed through a separation column where they are selectively retained. Intact living spermatozoa without DNA fragmentation pass through the column and are collected for later use (ICSI or cryopreservation).
Gain of the sperm ready for fertilization represents the key advantage over traditional DNA fragmentation tests in which patient obtain only impractical information on percentage of damaged cells. Similarly, methods for morphological assessing, like IMSI, cannot provide sufficient picture about the state of the DNA in the sperm nucleus.